Couplings simplify steam-in-place process
A
Colder Products product story
Edited by the Engineeringtalk editorial team
May 6, 2002
Colder Products has developed a novel Steam-Thru connection (STC) to streamline critical steam-in-place processes used in numerous biopharmaceutical applications.
Colder Products has developed a novel Steam-Thru connection (STC) to streamline critical steam-in-place processes used in numerous biopharmaceutical applications.
The STC serves the dual function of valve and connection, eliminating the costly and labour-intensive steps of traditional steam sterilisation processes.
This also speeds the connection process, and reduces the contamination risks associated with multiconnection steam-in-place applications.
Colder's STC enables biopharmaceutical companies to sterilise the flow path and initiate connections between a bioreactor and media bag without adding plumbing connections or additional steps to the process.
The uniquely designed STC uses a steam trap to rid the connection of steam during the sterilisation process.
This contrasts with traditional steam-in-place processes, which create "dead legs" where steam containing remnant micro-organisms become trapped in the connection chamber, increasing the chances of contamination.
"The disposable STC re-invents the steam-in-place process by eliminating connection steps, reducing validation concerns, and removing opportunities for contamination", said Carolyn Franceschi, Medical Business Unit Manager of Colder Products.
"The speed at which connections can now be made will streamline the new drug development process, yielding substantial savings for biopharmaceutical companies".
As a disposable device, the STC eliminates cleaning and process validation issues associated with re-useable connections.
These labour-intensive cleaning and validation processes introduce opportunities for both contamination and noncompliance with FDA regulations.
Traditional connection processes also require the use of capital equipment, such as a laminar flow hood, which increase the cost, time and space needed to make connections.
The STC works with existing systems without retrofit, enabling a seamless transition to this highly efficient steam-in-place process.
The device features industry standard terminations of 0.75in Mini and 1.5in Tri-clamp, and its 0.375 and 0.5in hose barbs connect to popular tubing sizes.
Not what you're looking for? Search the site.
Google Ads
Contact Colder Products
Related Stories
- Parker announces Par<>Fit filter elements
- Tank-cleaning rotary spray ball for CIP tasks
- Spiral hose range enhanced with size -40 model
- Pump Engineering offers aseptic control valve
- Trelleborg launches mechanical face seals
Articles by product category
- Consultancy and Services (903)
- Machine Building (4,517)
-
Engineering Design Software (6,179)
- Engineering Design Software (12)
- 2D CAD software (200)
- 3D CAD software (1,157)
- FEA and structural analysis software (369)
- Fluid, thermal, noise, vibration software (334)
- Simulation, modelling, validation software (914)
- Rendering, visualisation, styling software (196)
- Materials design and moulding design software (151)
- Process, instrumentation, automation software (258)
- Electrical design software (164)
- Publishing and documentation software (229)
- Maths, charting, statistics, QA software (317)
- Data, document management software (310)
- CAM, CNC, production management software (568)
- File conversion software, data capture (351)
- PLM and collaboration software (649)
-
Drives, Motors and Controls (3,361)
- Drives, Motors and Controls (1)
- Precision Motors and Gears (411)
- Industrial Drives/Controls (1,276)
- Linear Drives and Motors (114)
- Industrial Motors (497)
- Stepper and Servo Drives, Motors, Controls (1,060)
- Small Mechanical Components, Joining, Tools (1,975)
-
Control and Instrumentation (5,028)
- Plantwide control (1,324)
- Plant- and Machine-Wide Communications (1,174)
- Smaller-Sized PLCs (387)
- CNC and Motion Controllers (184)
- Mid-range and Large PLCs (201)
- Power Supplies, Uninterruptible Power (562)
- HMIs/Operator Interfaces (294)
- Logic Controllers, Timers and Relays (96)
- Cabling, Conduit, Signal Conditioning (806)
-
Monitoring, Measurement and Quality (5,459)
- Monitoring, Measurement and Quality (1)
- Data acquisition Software and Communications (494)
- Data Acquisition Hardware and PC I/O Boards (472)
- Electrical and Electronic Testing, PAT Equipment (630)
- Form/co-ordinate, optical, vision instruments (703)
- Gauges, Indicators and Instruments (440)
- Data loggers (422)
- Materials testing equipment (421)
- Telecomms/network test equipment, software etc (154)
- Testing and Calibration Services and Information (500)
- Testing, analysing and monitoring equipment (1,222)
-
Electrical and Electronic Equipment Design (4,160)
- Batteries, chargers and circuit protection (555)
- Connectors, Terminals, Busbars, Slip Rings (679)
- Enclosures and Equipment Cooling Fans (709)
- Knobs, Handles and Enclosure Hardware (420)
- PCs and Embedded Systems (798)
- Electrical and Electronic Subassemblies (369)
- Electrical and Electronic Components (630)
-
Materials and Processing (2,963)
- Materials and Processing (5)
- Materials and components (2,215)
- Rapid Prototyping (458)
- Materials processing and testing (285)
-
Engineering Industry News, Resources (6,093)
- Engineering Industry News, Resources (4)
- Engineering Business News, Views (388)
- Engineering Exhibitions, Events (562)
- Engineering Conferences (425)
- Engineering Seminars (400)
- Engineering Industry Developments, Awards (633)
- Engineering Guides, Newsletters (349)
- Engineering Recruitment, Employment (219)
- Engineering Training Courses (433)
- Engineering Education, Resources, Standards (838)
- Engineering Industry Reports, Surveys (597)
- Electronic Resources for Engineers (278)
- Health and Safety Legislation (402)
- Health and Safety Strategy, Risk Assessment (113)
- Health and Safety Consultancy, Software (175)
- Health and Safety Events, Training, News (277)
-
Powertrain Design (3,598)
- Powertrain Design (2)
- Bearings (939)
- Chains and belts (326)
- Gears, brakes, couplings and engines (1,441)
- Hydraulic Components (471)
- Lubricants (418)
-
Capital Equipment (3,387)
- Capital Equipment (1)
- Manufacturing Machinery and Plant Equipment (468)
- Production line blowers and fans (62)
- Compressors and Air Treatment (510)
- Electronics Manufacturing, Tools, Instruments (192)
- Electrical hardware (131)
- Machinery and Production Equipment (1,093)
- Robotics, Handling and Storage (930)
-
Sensors (7,080)
- Sensors (8)
- Accelerometers and Vibration Sensors (427)
- Loadcells, Force Sensors, Torque Sensors (699)
- Pressure sensors (621)
- Flowmeters and Flow Sensors (618)
- Level Sensors and Leak Detectors (527)
- Linear Position Sensors (399)
- Rotary Position, Tilt and Angular Sensors (546)
- Proximity Sensors (700)
- Gas, Chemical, Radiation, Magnetic Sensors (284)
- Humidity and Environmental Sensors (152)
- Temperature sensors (612)
- Vision and Colour Sensors (1,384)
- Barcode Sensors (103)
- Valves, Pumps, Process Hardware (3,623)
